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Stroke research · NeuroAI · Clinical translation

Better stroke decisions, from data to bedside.

We combine clinical data, neuroimaging, and computational methods to improve stroke prevention, treatment, and recovery.

Explore our research

Members of the Shu Lab gathering together

What we study

Three connected research areas

Across each area, we focus on results that can inform clinical care.

01

Risk & outcomes

We use large clinical datasets and multicenter collaborations to clarify risk, treatment, recurrence, and long-term outcomes across cerebrovascular care.

02

Clinical AI

We develop practical methods for turning imaging and unstructured health records into reliable, research-ready evidence.

03

Neurorecovery

We pair wearable sensing with machine learning to measure how stroke survivors use the affected arm in everyday activity.

Learn about our completed work →

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Clinical tools

Public decision-support tools derived from completed, peer-reviewed studies.

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30-day procedural risk

Peri-procedural Stroke Risk Calculator

Estimate individualized ischemic-stroke risk using the externally validated Brown model.

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1- and 3-year risk

DIAS³ Epilepsy Risk Calculator

Estimate epilepsy risk after cerebral venous thrombosis using the internationally validated DIAS³ score.

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Selected work

Recent publications

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2026

EHR-derived model for 30-day peri-procedural ischemic stroke

Journal of the American Heart Association · Read the paper

2026

Large language models for scalable stroke chart abstraction

American Journal of Neuroradiology · Read the paper

2024

DIAS³ score for epilepsy after cerebral venous thrombosis

JAMA Neurology · Read the paper

Work with us

Build better evidence for stroke care.

We welcome motivated trainees and collaborators.

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© 2026 Shu Lab · UPMC Department of Neurology

Stroke research · Clinical AI · Recovery

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